The ica Locus of Staphylococcus epidermidis Encodes Production of the Capsular Polysaccharide/Adhesin

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The ica locus of Staphylococcus epidermidis encodes production of the capsular polysaccharide/adhesin.

Clinical isolates of coagulase-negative staphylococci often elaborate a biofilm involved in adherence to medical devices and resistance to host defenses. The biofilm contains the capsular polysaccharide/adhesin (PS/A), which mediates cell adherence to biomaterials, and another antigen, termed polysaccharide intercellular adhesin (PIA), which is thought to mediate bacterial accumulation into cel...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1998

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.66.10.4711-4720.1998